From: Subject: Best Dx/Best Rx: Osteoporosis Date: Wed, 3 Jun 2009 21:25:18 -0700 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_01B2_01C9E491.CB38ADD0" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.5579 This is a multi-part message in MIME format. ------=_NextPart_000_01B2_01C9E491.CB38ADD0 Content-Type: text/html; charset="Windows-1252" Content-Transfer-Encoding: quoted-printable Content-Location: Best Dx/Best Rx: Osteoporosis


Elizabeth Holt, M.D., Ph.D.
Silvio E. = Inzucchi,=20 M.D.
Yale University School of Medicine

Defin= ition/Key=20 Clinical Features
Diffe= rential=20 Diagnosis
Best = Tests
Best = Therapy
Best = References

Definition/Key=20 Clinical Features

3D""bac= k to=20 top

Differential = Diagnosis

Other Diagnoses = to Consider=20 for Low Bone Density or Nontraumatic Fractures=20
3D""bac= k to=20 top

Best=20 Tests

Clinical=20 Pearls=20 Red Flags=20
3D""bac= k to=20 top

Best=20 Therapy

Modifiable Risk Factors=20

Drug Treatment for = Osteoporosis=20 Clinical Pearls=20
  • Reduce fracture risk through the following = measures:=20
    • Maintaining body weight=20
    • Weight-bearing physical exercise=20
    • Avoiding drugs that may cause sedation or = falls=20
    • Treating impaired vision=20
    • Hip protectors have been shown to be = effective in some=20 clinical trials
  • Osteoporosis in men is idiopathic in about = half of=20 cases; identifiable causes include the following:
    • Hypogonadism=20
    • Alcohol abuse=20
    • Liver or intestinal disease =
  • Men benefit from calcium repletion, adequate = vitamin D=20 intake, appropriate exercise regimen, and antiresorptive agents, if=20 applicable

    3D""bac= k to=20 top

    Best = References

    Body JJ, et al: J Clin Endocrinol Metab 87:4528, = 2002 [PMID=20 12364430]

    Liberman UA, et al: N Engl J Med 333:1437, 1995 = [PMID=20 7477143]

    Maricic M, et al: Arch Intern Med 162:1140, 2002 = [PMID=20 12020184]

    McClung MR, et al: N Engl J Med 344:333, 2001 = [PMID=20 11172164]

    NIH Consensus Panel: JAMA 285:785, 2001 [PMID=20 11176917]

    Women's Health Initiative Investigators: JAMA = 288:321, 2002=20

    July=20 2006

    =A9 = 2006 WebMD,=20 Inc.=20